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Funding: Addressing Opioid Crisis: NIH Helping to End Addiction Long-term (HEAL)SM Initiative

Deadline: Friday, February 1, 2019

Funding: Addressing Opioid Crisis: NIH Helping to End Addiction Long-term (HEAL) SM Initiative – Apply by 2/1/2019.

A part of the NIH HEAL (Helping to End Addiction Long-term) Initiative, the HEAL Pain Management Effectiveness Research Network (ERN) works to support research across the NIH to improve treatments for opioid misuse and addiction and enhance pain management. Proposals should address pain management by supporting clinical trials that compare the effectiveness of existing therapies, including combinations or novel approaches using existing therapies, to prevent or manage pain in ways that reduce the risk of addiction. Clinical trials will be conducted within the existing NCATS CTSA Program – Trial Innovation Network. Applications due Feb. 1.

Things you need to know:

  • Due to the timing of the HEAL Pain Management ERN FOA and to avoid any conflicts of interest, the Trial Innovation Network (TIN) will not accept proposals requesting initial consultations for RFA-NS-19-021.
  • The Trial Innovation Network (TIN) will provide data coordination services, clinical coordination services, single IRB functions, biostatistical support, and recruitment and retention support for awarded studies. Those submitting applications in response to RFA-NS-19-021 do not need to request these resources.
  • The TIN will work with the broad consortium of Clinical and Translational Science Awards (CTSA) Program hubs and other sites identified by awardees to implement studies.
  • Given the compressed timeframe to prepare an application in response to RFA-NS-19-021 and the expected high volume of cohort discovery requests, the TIN will not accept formal requests for Trial Innovation Network electronic health record (EHR)-based cohort assessments for this RFA using the traditional TIN proposal form. Instead, applicants to RFA-NS-19-021 seeking CTSA Program hub clinical sites for pain clinical trials should contact the HEAL CTSA Program point of contact (POC) directly (see below). This person will provide information about local pain expertise and approximately how many participants might be available for a trial at their site.

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