PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) has recently announced a funding opportunity that will provide up to $3 million in direct costs for studies up to three years long that compare the effectiveness of interventions (e.g., specific pharmacologic and/or behavioral interventions) that address mental health conditions in individuals with intellectual and developmental disabilities (IDD). This can be randomized control trials (RCT) or an observational study.

For more information or to request a brief consultation, please contact Leslie MacGregor, PCORI Funding Specialist: Leslie_MacGregor@hms.harvard.edu

Question of interest

What is the comparative effectiveness of evidence-based or commonly used approaches (e.g., specific pharmacologic and behavioral interventions) that address mental health conditions in individuals with IDD?​

Population

Individuals with both IDD and mental health conditions

Interventions/Comparators

Head-to-head comparisons of evidence-based interventions that target mental health conditions in individuals with IDDs

Outcomes

Symptom severity, functional impairment, quality of life, adverse events, health resource utilization, relevant caregiver outcomes, and related outcomes

Funding

Total allocated for this PFA: Up to $40 million in total costs
Total direct funding: $3 million

Maximum project duration

Three years

Important dates

January 11 – Applications open
January 31 – Town Hall
February 8 – Letters of Intent due
May 3 – Applications due
July 2022 – Merit review
December 2022 – Awards announced
March 2023 – Earliest start date