Funding: The Center of Research Translation on Osteoporosis Bone Anabolic Therapies Pilot & Feasibility Research Proposals

The Center of Research Translation on Osteoporosis Bone Anabolic Therapies (CORT), based in the Endocrine Unit at Massachusetts General Hospital, and funded by the National Institute of Arthritis and Musculoskeletal Diseases (NIAMS) P50 mechanism is announcing a request for Pilot and Feasibility Research proposals ($30,000/year direct costs plus 20% indirect costs). This announcement is directed to faculty proposing highly focused research projects that address mechanisms of action of osteoporosis bone anabolic therapies using preclinical or clinical models. Specifically, pilot and feasibility funding is encouraged to be used to support development of novel technologies that contribute to this goal. Awardees will be expected to present progress to CORT members biannually and provide a written annual report.

Letter of intent should include:

• A 250-word abstract
• NIH style biosketch
• other support page

Investigators must invest at least .50 calendar months of effort. If salary requests do not reflect this effort, cost-sharing plans must be indicated. Applicants who are not U.S. citizens or permanent U.S. residents must have active visas permitting them to remain in the U.S. for the full period of the proposed research.

Per NIAMS rules, interventional clinical studies are not allowed.

Previous P50 P&F awardees will be allowed to re-apply for an additional year of funding.

Deadline & Submission information:

• LOI deadline: September 26, 2025 at 5:00pm EST
• Please submit in a single PDF file to dafitzgerald@mgb.org. In subject line, include your last name and “P50P+F LOI”.
• Those invited to apply for funding will be informed by October 3, 2025.