Search de-identified data from clinic visits at several Harvard-affiliated hospitals. SHRINE

At a glance

Key Features
Request aggregate numbers of patients seen at participating hospitals who meet criteria of interest
Useful for
  • Characterizing potential clinical trial cohorts
  • Generating new research hypotheses
  • Conducting research requiring large sample sizes (e.g., population health studies)

Harvard SHRINE Network

The Harvard SHRINE Network was decommissioned in May 2018. Soon, many Harvard-affiliated researchers will have access to the ACT Network, the largest national SHRINE network to date. To learn more about the ACT Network, visit the ACT website. For more information about potential alternatives, please contact your home institution.

SHRINE software will continue to be actively developed. It will remain in use as open source and as a platform for other networks such as ACT.

What is SHRINE?

The Shared Health Research Information Network (SHRINE) helps researchers overcome one of the greatest problems in population-based research: Compiling large groups of well-characterized patients. Eligible investigators may use the SHRINE web-based query tool to determine the aggregate total number of patients at participating hospitals who meet a given set of inclusion and exclusion criteria (currently demographics, diagnoses, medications, and selected laboratory values). Because counts are aggregate, patient privacy is protected.

These data will be most useful for investigators interested in:

  • Generating new research hypotheses
  • Planning research requiring large sample sizes not easily available at any single institution
  • Preparing grant applications that would benefit from pre-identification and/or characterization of a potential research cohort
  • Identifying potential cohorts for clinical trials
  • Conducting research in the areas of population health and health services

Participating Institutions

  • Beth Israel Deaconess Medical Center (BIDMC)
  • Boston Children's Hospital (BCH)
  • Brigham and Women's Hospital (BWH)
  • Dana-Farber Cancer Institute (DFCI)
  • Massachusetts General Hospital (MGH)