Supporting innovation and teams in diagnostics, prevention, biomarkers, and therapeutics. Reactor: Accelerating Clinical and Translational Research

The Reactor Team

Eva C. Guinan, MD
Professor of Radiation Oncology
Harvard Medical School
Director of Translational Research
DFCI/BWH Department of Radiation Oncology
Director, Reactor, Harvard Catalyst

Eva Guinan, MD, is a pediatric hematologist/oncologist and an international expert in bone marrow failure and stem cell transplantation. She graduated from Harvard College and Harvard Medical School. She has been the senior investigator for clinical trials in human stem cell transplantation, as well as innovative proof of concept studies arising from her laboratory work where she developed the use of novel biological approaches to the problem of mismatched transplantation. She and her collaborators have discovered a radiation mitigation strategy that may be suitable for use after unintended radiation exposures such as Fukishima and Chernobyl, or to moderate therapeutic radiation toxicity. To pursue that research and put her background in clinical/translational research to full use, she joined the Department of Radiation Oncology at the DFCI as its first director of Translational Research. She is also the director of the Harvard Catalyst Reactor program which works to initiate novel approaches to important clinical questions and to implement empiric experiments designed to explore whether distributed innovation techniques, alternative evaluation approaches, and novel concepts in team formation can be effective within the academic biomedical community.

Anthony N. Hollenberg, MD
Chief, Division of Endocrinology, Diabetes and Metabolism
Beth Israel Deaconess Medical Center (BIDMC)
Professor of Medicine, HMS

Anthony Hollenberg, MD, received his MD from the University of Calgary in Canada in 1986. He completed his internal medicine residency in 1989 and was chief resident in medicine from 1990-1991, both at the BIDMC. Hollenberg then completed a fellowship in endocrinology, diabetes, and metabolism at Massachusetts General Hospital in 1993 and was recruited back to BIDMC to start his laboratory. Hollenberg's research focuses on the hormonal regulation of metabolism, with a particular emphasis on the role of thyroid hormone. His work has important ramifications for the regulation of body weight and metabolism.

Gary S. Gray, PhD
Director of Technology and Innovation
Harvard Catalyst

Gary S. Gray has a long-standing interest in human healthcare and a desire to improve it by investigating novel disease pathways and potential drug targets, discovering therapeutics to attack these pathways and targets, and then translating these discoveries into clinical practice. As a basic researcher, Gray has led a variety of drug discovery efforts in biotechnology and pharmaceutical companies. Drugs discovered by his group transitioned from discovery to formal clinical development. During the last 12 years as a project leader, Gray achieved a demonstrated record of accomplishment building and leading multidisciplinary, cross-functional teams in translational medicine. In addition, he has provided research and development expertise in evaluating program licensing opportunities, and has served on numerous diligence teams supporting mergers and acquisitions within business development.

Brian M. Clancy, PhD
Research Scientist Project Manager
Reactor, Harvard Catalyst

Brian M. Clancy works with the leaders and members of multiple translational research teams to establish the overall project plan, set timelines, and define project deliverables to ensure projects are executed on budget, on schedule, within scope, and with the highest quality. Clancy has a long-standing interest in translating basic science discoveries into medical products. He has extensive experience leading and managing multidisciplinary, cross-functional teams of scientists in discovery research at a global pharmaceutical company. In addition to his extensive background in biomedical research, he has a Project Management Professional (PMP) certificate from the Project Management Institute.

Hardeep Ranu
Project Manager
Reactor, Harvard Catalyst

Hardeep Ranu is a project manager for Reactor and is responsible for managing a diverse set of clinical and translational research project teams. Hardeep joined Harvard Catalyst from Harvard T.H. Chan School of Public Health, where she managed the TaqMan genotyping core for 13 years. As the genotyping project manager, Hardeep worked with faculty of Harvard Medical School, Chan School of Public Health, HMS affiliated hospitals, and external institutions to design and develop genotyping projects. Her role as genotyping project manager involved coordinating with two funding entities, the Dana-Farber/Harvard Cancer Center (DF/HCC) and Partners Healthcare|Personalized Medicine as well as working with senior management and faculty from DF/HCC to write and prepare reports for DF/HCC submissions and renewals.
Hardeep earned her PhD in Biochemistry/Pharmacology at Imperial College School of Medicine, University of London, and completed postdoctoral research at National Heart & Lung Institute, Imperial College of Medicine, London, and Massachusetts General Hospital.

Kate McGroarty
Project and Events Coordinator
Harvard Catalyst

Kate McGroarty is the Project and Events Coordinator for all of Harvard Catalyst. In this capacity, she assists the Reactor program with the planning, coordination, and execution of educational events and symposia. Previously she has worked for Loyola University Chicago and project managed the Chicago non-profit scienceFIST, dedicated to bringing after school science programs to at-risk youth. Kate received her bachelor's degree from Northwestern University in Chicago.

Francie Sullivan
Staff Assistant
Reactor, Harvard Catalyst

Francie Sullivan is the Staff Assistant for both the Reactor and Operations teams at Harvard Catalyst. Previously, she worked in the development team as a Community Ambassador for the United Way of Massachusetts Bay and Merrimack Valley, a national non-profit. Francie is originally from Baltimore, Maryland, and received her bachelor's degree from the College of the Holy Cross in Worcester, Massachusetts.