- An introduction to the principles and practice of T1 translational research
|Courses on the principles & practices of translational research.||Introduction to Translational Medicine|
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Utilizing both case studies and a didactic curriculum, Introduction to Translational Medicine (ITTM) is a survey course that offers an introduction to the skills necessary to embark on a career in translational research, particularly in the process of bringing an idea from the laboratory to first-in-human trials (called T1 translational research). This course focuses on the principles and practices of translational medicine as they apply to the development of a new drug (small molecules and/or biologics), device, or diagnostic. Case studies allow participants to grasp the realization of the concepts discussed. Each attendee receives training in the pre-clinical development of novel targets and leads, clinical pharmacology, the regulatory process, and design of the first-in-human clinical trial. In addition, participants learn about funding opportunities for translational research, as well as how to navigate academic/industrial collaborations that lead to the successful development of new drugs or methodologies.
All course materials, including presentations by the faculty, and required and supplemental readings, are made available to attendees in advance of the course. It is expected that all attendees will complete required readings and assignments before the course begins.
Learning about the T spectrum (T1-T4 phases of research) is critical to understanding clinical and translational research. Watch a Harvard Catalyst video that demonstrates these phases.
Watch a Pathfinder video in which ITTM presenter Mason Freeman, MD, explains T1 translational research.