The program offers a three-module course series that covers both general and specialized topics in translational genetics, and is designed to better acquaint clinicians and scientists with the tools and technologies of genetics and genomics.

Participants are encouraged, but not required, to sign up for the three courses in series.

Module 1:

Welcome to the Genetic Code: An Overview of Basic Genetics

This introductory course will review fundamental language and concepts including DNA anatomy and genome organization; genotype-phenotype correlations; basic population genetics; and genotyping. Participants will have the opportunity to submit questions to the faculty prior to the lectures.

This course is strongly recommended for both new and experienced clinicians, clinical investigators, nurses, and other clinical research staff who wish to further expand their knowledge of modern concepts in genetics and genomics.

Faculty:

LMA: Augusto Litonjua, Assistant Professor of Medicine, Channing Laboratory, BWH; and Benjamin Raby, Assistant Professor of Medicine, Channing Laboratory, BWH

MGH: Jordan Smoller, Associate Professor of Psychiatry, Center for Human Genetic Research, MGH; and Susan A. Slaugenhaupt, Associate Professor of Neurology, Center for Human Genetic Research, MGH

Lecture Topics:
• DNA Anatomy and Genome Organization
• Genotype-Phenotype Correlations
• Basic Population Genetics
• Genotyping

This module is offered collaboratively by Harvard Catalyst, the Center for Clinical Investigation at Brigham and Women’s Hospital, and the Clinical Research Program at Massachusetts General Hospital.

This course was offered on February 6, 2012, at Massachusetts General Hospital.*

This course was offered February 16, 2012, at Brigham and Women's Hospital.**

Please check back for future offerings of this course.

*This program meets the requirements of the Board of Registration in Nursing, at 244 CMR 5.00, for 2 contact hours of nursing continuing education.

Course Director: Eric Rosenberg, MD, Co-Director, Education Unit, Clinical Research Program, MGH

This course is part of a CME series in Genetics and Genomics which also includes courses in Pharmacogenomics, Genetic Literacy, and Sequencing. Upon completion of this CME series, participants will be able to: utilize basic concepts of genetics and genomics in the conduct of clinical research.

The Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Harvard Medical School designates this live activity for a maximum of 2.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

**Course Director: Gordon Williams, MD, CCI Program Director

Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Harvard Medical School designates this live activity for a maximum of 4 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Module 2:

Genetic Literacy: An Intermediate Guide to Understanding the Language and Concepts of Modern Genetic Research

What's a SNP? What's the HapMap? What is a microarray and is it used for genotyping or gene expression analysis? What's an association study (and why do they do it)? If you find yourself asking similar questions, come to this course designed to briefly describe the terminology, technologies, and methodologies of modern genetics.

This second module of the series is intended for individuals with basic knowledge of modern concepts of genetics and genomics or who have taken Module 1.

This module is offered collaboratively by Harvard Catalyst, the Center for Clinical Investigation at Brigham and Women’s Hospital, and the Clinical Research Program at Massachusetts General Hospital.

Faculty:

LMA: Augusto Litonjua, Assistant Professor of Medicine, Channing Laboratory, BWH; and Benjamin Raby, Assistant Professor of Medicine, Channing Laboratory, BWH

MGH: Jordan Smoller, Associate Professor of Psychiatry, Center for Human Genetic Research, MGH; Ben Neale, Instructor, Analytic and Translational Genomics Unit, MGH and Susan A. Slaugenhaupt, Associate Professor of Neurology, Center for Human Genetic Research, MGH

Lecture Topics:
• Intro to Association Studies (a discussion of SNPs, haplotypes, LD, etc)
• Case-control and Family-based Association Studies
• Genome-wide Association Studies
• Use of Databases

Additional expert faculty will be added to cover specific topics.

This course will be offered on March 28, 2012, at Massachusetts General Hospital.*

Registration is required. Click here to register for Genetic Literacy at MGH. Please contact Suzanne Powell with any questions.

This course will also be offered March 29, 2012, at Brigham and Women's Hospital.**

Registration is required. Click here to register for Genetic Literacy at BWH. Please contact Lisa Horton with any questions.

*This program meets the requirements of the Board of Registration in Nursing, at 244 CMR 5.00, for 2 contact hours of nursing continuing education.

Course Director: Eric Rosenberg, MD, Co-Director, Education Unit, Clinical Research Program, MGH

This course is part of a CME series in Genetics and Genomics which also includes courses in Pharmacogenomics, Genetic Literacy and Sequencing. Upon completion of this CME series, participants will be able to: utilize basic concepts of genetics and genomics in the conduct of clinical research.

Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Harvard Medical School designates this live activity for a maximum of 2.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

**Course Director: Gordon Williams, MD, CCI Program Director

Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Harvard Medical School designates this live activity for a maximum of 4 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Module 3:

A Primer on Complex Trait Genetics: Principles for the Clinical Investigator
Are you able to keep up with the changing face of genetic research? Have you heard of disease areas that have seen explosive growth in genetic discoveries in the past year? This is an excellent opportunity to learn the essential elements of complex trait genetics and gain the latest insights from expert faculty from the Center for Human Genetic Research and the Broad Institute of Harvard and MIT.

Wednesday, April 4, 2012
8:00am-4:00pm
Massachusetts General Hospital
Simches Research Building
Room 3.110
185 Cambridge Street, Boston

There is no cost to attend this symposium, but registration is required. Click here to register. Please contact Suzanne Powell with any questions.

**Please note: This course will be videotaped.**

Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Harvard Medical School designates this educational activity for a maximum of 6.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This module is offered collaboratively by Harvard Catalyst, the Broad Institute of MIT and Harvard, and the Center for Human Genetic Research and Clinical Research Program at Massachusetts General Hospital.