Events in October 2010

  • October 4, 2010

    arrow-rightIntroduction to Clinical Investigation

    Location: Sheraton Commander Hotel, Cambridge

    This course offers an introduction to the skills necessary to embark on a career in clinical research. By providing a survey experience in core competency areas using a mixture of didactic lectures and workshops, attendees will be challenged to move beyond rote repetition of learned material. Participants will enhance their ability to analyze, synthesize, and evaluate data along the translational research continuum of:

    • T1 (first-in-human/proof of
      concept research)
    • T2 (definitive clinical trials to change
      the standard of care)
    • T3 (practice-based research)
    • T4 (population-based research)

    For more information, or to submit an application, visit the ICI page.

  • October 5, 2010

    arrow-rightIntroduction to Clinical Investigation

    Location: Sheraton Commander Hotel, Cambridge

    This course offers an introduction to the skills necessary to embark on a career in clinical research. By providing a survey experience in core competency areas using a mixture of didactic lectures and workshops, attendees will be challenged to move beyond rote repetition of learned material. Participants will enhance their ability to analyze, synthesize, and evaluate data along the translational research continuum of:

    • T1 (first-in-human/proof of
      concept research)
    • T2 (definitive clinical trials to change
      the standard of care)
    • T3 (practice-based research)
    • T4 (population-based research)

    For more information, or to submit an application, visit the ICI page.

  • October 6, 2010

    arrow-rightIntroduction to Clinical Investigation

    Location: Sheraton Commander Hotel, Cambridge

    This course offers an introduction to the skills necessary to embark on a career in clinical research. By providing a survey experience in core competency areas using a mixture of didactic lectures and workshops, attendees will be challenged to move beyond rote repetition of learned material. Participants will enhance their ability to analyze, synthesize, and evaluate data along the translational research continuum of:

    • T1 (first-in-human/proof of
      concept research)
    • T2 (definitive clinical trials to change
      the standard of care)
    • T3 (practice-based research)
    • T4 (population-based research)

    For more information, or to submit an application, visit the ICI page.

  • October 6, 2010

    arrow-rightPerl and BioPerl for biologists

    Time: 09:30 AM - 4:30 PM

    Location: Lower Level, Room 025, Countway Library, 10 Shattuck Street, Boston

    This workshop gives an overview of Perl, with a quick introduction to BioPerl. Participants will learn to read and modify Perl scripts, as well as write small scripts of their own. Special focus is given to reading, filtering, and reformatting scientific data. Because the workshop lasts only one day, we do not have time to introduce the basic concepts of programming, such as loops, conditions, and variables. Anyone who has programmed even a small amount in any programming language should be comfortable, but others are encouraged to take a more extensive class. The examples are all biology-related, but biology training is not needed for the class.

    Click here to register.

  • October 7, 2010

    arrow-rightIntroduction to Clinical Investigation

    Location: Sheraton Commander Hotel, Cambridge

    This course offers an introduction to the skills necessary to embark on a career in clinical research. By providing a survey experience in core competency areas using a mixture of didactic lectures and workshops, attendees will be challenged to move beyond rote repetition of learned material. Participants will enhance their ability to analyze, synthesize, and evaluate data along the translational research continuum of:

    • T1 (first-in-human/proof of
      concept research)
    • T2 (definitive clinical trials to change
      the standard of care)
    • T3 (practice-based research)
    • T4 (population-based research)

    For more information, or to submit an application, visit the ICI page.

  • October 7, 2010

    arrow-rightCardiovascular Imaging

    Time: 08:30 AM - 12:00 PM

    Location: Room 3.120, Simches Research Building, MGH, 185 Cambridge St., Boston

    The cardiovascular imaging module reviews state of the art applications of cardiovascular ultrasound, magnetic resonance imaging, computed tomography, and nuclear imaging in clinical research. Participants will also learn about the basic principles of the use of imaging biomarkers and the life cycle of medical imaging data.

    Click here to register.

  • October 8, 2010

    arrow-rightIntroduction to Clinical Investigation

    Location: Sheraton Commander Hotel, Cambridge

    This course offers an introduction to the skills necessary to embark on a career in clinical research. By providing a survey experience in core competency areas using a mixture of didactic lectures and workshops, attendees will be challenged to move beyond rote repetition of learned material. Participants will enhance their ability to analyze, synthesize, and evaluate data along the translational research continuum of:

    • T1 (first-in-human/proof of
      concept research)
    • T2 (definitive clinical trials to change
      the standard of care)
    • T3 (practice-based research)
    • T4 (population-based research)

    For more information, or to submit an application, visit the ICI page.

  • October 8, 2010

    arrow-rightThe 3rd Annual BIDMC Cancer Symposium: Prostate Cancer and the Molecular Genetics of Cancer

    Time: 08:00 AM - 5:00 PM

    Location: Joseph B. Martin Conference Center, Harvard Medical School, 77 Avenue Louis Pasteur, Boston

    Sponsored by the Cancer Center at Beth Israel Deaconess Medical Center, this symposium will feature a panel of speakers from across the United States speaking on the recent developments in prostate cancer genetics and their translational impact.

    Seating is limited, and registration required. For more information (including a list of speakers), or to register, visit the symposium website.

  • October 12, 2010

    arrow-rightEnsembl genome browser workshop

    Time: 10:30 AM - 12:30 PM

    Location: Lower Level 2, Room 025, Countway Library, 10 Shattuck Street, Boston

    Ensembl provides unified access to genomic information and annotation for more than 50 eukaryotic species. Learn how to find what you need, from splice sites to regulatory regions to SNPs. We'll also explore the BioMart tool to select and export Ensembl data. With hands-on exercises.

    Click here to register.

  • October 12, 2010

    arrow-rightHigh-throughput microarray analysis in a cluster environment

    Time: 1:00 PM - 3:00 PM

    Location: Room 403, Countway Library, 10 Shattuck Street, Boston

    Computers running large dataset in R can sometimes encounter problems with memory, which can be a very frustrating experience. The workshop will cover on how to carryout microarray analysis in a high performance cluster environment including how to install R and Bioconductor libraries in the cluster environment. Running a R job both interactively and remotely to retrieve the desired results will also be taught. Students will learn how to carry out the following: quality control, normalization, filtering, statistical analysis, differential expression using limma, and clustering analysis of Affymetrix data. Please note: You will need a login account for the HMS Orchestra cluster to carry out the hands-on exercises. Visit this link to obtain an account.

    Click here to register.

  • October 12, 2010

    arrow-rightBLAST tips and tricks

    Time: 3:00 PM - 4:00 PM

    Location: Ballard Room, 5th Floor, Countway Library, 10 Shattuck Street, Boston

    Learn how to use BLAST as an experimental tool. We will cover the use of filters as BLAST tools and contrast them with the use of PHI-BLAST. We will learn about substitution matrices and how the PSSM relates to PSI-BLAST. We will discuss how to avoid doing a BLAST search and still obtain the relevant information.

    Click here to register.

  • October 13, 2010

    arrow-rightImaging in Oncology

    Time: 1:00 PM - 5:00 PM

    Location: Sherman Auditorium, BIDMC, 330 Brookline Ave., Boston

    This module covers all modalities used for clinical and preclinical imaging in oncology. Among other topics, emphasis is put on the role of imaging for clinical trials, the use of biomarkers in quantitative imaging, and metabolic response assessment.

    Click here to register.

  • October 14, 2010

    arrow-rightMayo Clinic CTSA Exercise Symposium

    Location: Mayo Clinic, Rochester, Minn.

    The Mayo Clinic Center for Translational Science Activities (CTSA) will host an exercise science symposium at the Mayo Clinic campus in Rochester, Minn., on October 14-15, 2010.

    The symposium will touch on a wide variety of exercise-related topics, from the science of mitochondrial energy metabolism to mind-body interactions to the use of exercise in patient care.

    Click here for more information.

  • October 15, 2010

    arrow-rightMayo Clinic CTSA Exercise Symposium

    Location: Mayo Clinic, Rochester, Minn.

    The Mayo Clinic Center for Translational Science Activities (CTSA) will host an exercise science symposium at the Mayo Clinic campus in Rochester, Minn., on October 14-15, 2010.

    The symposium will touch on a wide variety of exercise-related topics, from the science of mitochondrial energy metabolism to mind-body interactions to the use of exercise in patient care.

    Click here for more information.

  • October 18, 2010

    arrow-rightBoston University CTSI IDE workshop

    Time: 09:00 AM - 12:00 PM

    Location: Room L109ABC, BU School of Medicine Instructional Building, 72 East Concord Street, Boston

    What do I need to know when studying medical devices? Best Practices for Preparation and Maintenance of Sponsor-Investigator IDEs

    Jelena P. Berglund, PhD, RAC
    Associate Director, Regulatory Affairs
    DTMI

    The Boston University Clinical & Translational Science Institute (BU CTSI), in collaboration with the Duke Translational Medicine Institute (DTMI), is pleased to announce two special workshops on investigational new drugs and devices for clinical researchers at NIH-funded clinical and translational science centers in Massachusetts, including Harvard Catalyst.

    Clinical investigators and other study team members responsible for submitting and maintaining IND and IDE applications to the US Food and Drug Administration should consider attending.

    There is no cost to attend these events, but pre-registration is required. For more information, or to register, visit the website of BU Medical Center's Clinical Research Resources Office.

  • October 18, 2010

    arrow-rightThe BRI Interdisciplinary Research Workshop: “Inflammation: Shared Mechanisms of Disease”

    Time: 1:00 PM - 5:30 PM

    Location: The Rotunda, New Research Building, Harvard Medical School, 77 Avenue Louis Pasteur, Boston

    This event is part of the Interdisciplinary Research Workshop series hosted by the Biomedical Research Institute (BRI) at Brigham and Women’s Hospital. These workshops bring investigators together and foster collaborative research.

    All members of the Harvard research community are welcome to attend. Registration is required, and CME credits are available. For more information, including a list of speakers, or to register for this event, visit the conference website.

  • October 18, 2010

    arrow-rightNeuroimaging

    Time: 2:00 PM - 5:00 PM

    Location: Room 3.120, Simches Research Building, MGH, 185 Cambridge St., Boston

    Frontiers of clinical neuroimaging are explored in this course. The neuroimaging module reviews neuropsychiatric applications of magnetic resonance imaging, computed tomography, and nuclear imaging in clinical research. Participants will also learn about the basic principles of the use of neuroimaging biomarkers.

    Click here to register.

  • October 18, 2010

    arrow-rightThe 17th Annual Dr. J. Murray Gavel Clinical Research Lecture

    Time: 5:00 PM - 7:30 PM

    Location: The Forsyth Institute, 245 First Street, 17th floor, Cambridge

    The 17th Annual Dr. J. Murray Gavel Clinical Research Lecture: Management of Inflammation in Periodontitis

    Thomas Van Dyke, DDS, PhD
    Vice President for Clinical Research
    Chair, Department of Periodontology
    The Forsyth Institute

     

    The Dr. J. Murray Gavel Clinical Research Lectureship, presented annually by The Forsyth Institute, perpetuates Dr. Gavel’s legacy of leadership and commitment to lifelong education by recognizing outstanding contributions to clinical research in oral disease care. Since its inception in 1994, this lectureship has invited prominent speakers who represent the ideals of the late Dr. Gavel in the areas of dentistry, medicine, academia, or research that have had a significant impact on the oral health of the public.

    Advance registration is required to attend this event, as space is limited. For more information, or to register, contact Pamela Quattrocchi (E-mail, 617-892-8604).

  • October 19, 2010

    arrow-rightFrontiers in Mucosal Immunity Conference: "The Microbiome in Health and Disease”

    Time: 08:00 AM - 5:00 PM

    Location: The Rotunda, Joseph B. Martin Conference Center, Harvard Medical School, 77 Avenue Louis Pasteur, B

    The Harvard Digestive Diseases Center invites you to their biannual Frontiers in Mucosal Immunity Conference, an opportunity for scientists and students from academic institutions throughout New England to present their work and discuss research pertaining to all aspects of mucosal immunology.

    The event will feature a how-to/boot camp on detailing how to collect samples for microbiome analyses, undertake the bioinformatics, and validate findings in germfree mouse systems.

    Lunch will be provided to conference registrants. To pre-register, contact Anneka Werner-Gavrin (E-mail).

  • October 19, 2010

    arrow-rightBoston University CTSI IND workshop

    Time: 09:00 AM - 12:00 PM

    Location: Room L109ABC, BU School of Medicine Instructional Building, 72 East Concord Street, Boston

    What do I need to know when studying investigational drugs? Best Practices for Preparation and Maintenance of Sponsor-Investigator INDs

    Erin K. O’Reilly, PhD, RAC
    Associate Director, Regulatory Affairs
    DTMI

    The Boston University Clinical & Translational Science Institute (BU CTSI), in collaboration with the Duke Translational Medicine Institute (DTMI), is pleased to announce two special workshops on investigational new drugs and devices for clinical researchers at NIH-funded clinical and translational science centers in Massachusetts, including Harvard Catalyst.

    Clinical investigators and other study team members responsible for submitting and maintaining IND and IDE applications to the US Food and Drug Administration should consider attending.

    There is no cost to attend these events, but pre-registration is required. For more information, or to register, visit the website of BU Medical Center's Clinical Research Resources Office.

  • October 20, 2010

    arrow-rightNeuroimaging

    Time: 1:00 PM - 5:00 PM

    Location: Sherman Auditorium, BIDMC, 330 Brookline Ave., Boston

    Frontiers of clinical neuroimaging are explored in this course. The neuroimaging module reviews neuropsychiatric applications of magnetic resonance imaging, computed tomography, and nuclear imaging in clinical research. Participants will also learn about the basic principles of the use of neuroimaging biomarkers.

    Click here to register.

  • October 22, 2010

    arrow-rightHow to identify microRNA targets, work with microRNA data, and use predicted information

    Time: 1:00 PM - 3:00 PM

    Location: Room 403, Countway Library, 10 Shattuck Street, Boston

    MicroRNAs (miRNAs) regulate gene expression by directly binding to messenger RNA sequences leading to the repression of protein translation. It is has been hypothesized that identifying patterns of miRNA expression in disease states and elucidating the processes dictated by their targets will be key defining mechanisms of disease progression or classification. Here we use MetaCore in combination with MetaLink to visualize and characterize the biological functions of miRNA (from breast cancer subtypes) and their novel, known, or predicted targets. Learn how to create interaction file types to be used in conjunction with expression analysis to first identify sets of miRNA for each cancer subtype then exploit our network building algorithms to build expanded networks for each set of microRNA. In this session you will also learn how to expand beyond the direct interactions of miRNA and their targets to export gene lists of associated biological functions for further enrichment analysis and comparison of function between cancer subtypes defined by miRNA trends. Also exploit how to use your miRNA target network as your own ontology for enrichment of a list of new targets. Lastly, learn how to overlay gene expression data from aggressive tumor samples to demonstrate a causative relationship with changes miRNA expression and target expression.

    Click here to register.

  • October 26, 2010

    arrow-rightThe Autism Consortium Annual Symposium

    Time: 08:00 AM - 5:00 PM

    Location: Joseph B. Martin Conference Center, HMS, 77 Aveune Louis Pasteur, Boston

    This annual event of the Autism Consortium brings together a unique collaboration of scientists, clinicians, donors, and families, who are working to catalyze rapid advances in understanding, diagnosis and treatment of autism and to broadly share their work.

    This year’s Symposium will include speakers on the following topics:

    • Informatics in Autism Research, focusing on the Consortium’s repository of phenotypic data and biological samples for nearly 500 families
    • New Advances in Early Screening and Diagnostics, focusing on two new approaches
    • The Promise of Translational Medicine in ASD, including clinical trials underway
    • Developments in Autism Genetics, including deep resequencing and clinical testing

    There will be a poster session during lunch.

    There is no cost for this event. For the full agenda and to register for this event, visit the symposium website. For more information, contact the Autsim Consortium (E-mail, 617-432-6961).

  • October 26, 2010

    arrow-rightIntroduction to microarrays and Affymetrix data analysis using R/Bioconductor

    Time: 1:00 PM - 3:00 PM

    Location: Room 403, Countway Library, 10 Shattuck Street, Boston

    The course is a general introduction to microarrays and the use of R/Bioconductor to carry out microarray data analysis. Following introduction the workshop starts with hands-on exercise on how to install R and Bioconductor GUI packages. The course is mainly based on the use of Bioconductor open source packages for analyzing single channel. R coding skill is not required since all the analysis are performed using AffylmGUI, LimmaGUI, and OneChannelGUI, a graphical interface to Bioconductor tools, designed for life scientists who are not familiar with R language. Students will learn how to carryout the following: quality control, normalization, filtering, statistical analysis, differential expression, and clustering analysis of Affymetrix data.

    Click here to register.

  • October 27, 2010

    arrow-rightAn overview of REDCap: A free, web-based data management & survey tool

    Time: 2:00 PM - 3:00 PM

    Location: Duncan Reid Conference Room, BWH, 75 Francis Street, Boston

    Come learn about Research Electronic Data Capture (REDCap) and REDCap Survey, two free, web-based data management tools available to Harvard investigators through the Harvard-affiliated academic health care centers. Using REDCap, investigators can create and design projects using:

    • A web browser-based Online Form Editor; and/or
    • An offline method by constructing and uploading a "data dictionary" template file in Microsoft Excel.

    Lynn Simpson, a electronic data capture (EDC) support specialist based in Partners Research Computing’s Enterprise Research Infrastructure and Systems group, will present a system summary on how to utilize the tools to build and manage online databases and surveys. This event is sponsored collaboratively by the Center for Clinical Investigation at Brigham and Women’s Hospital and Harvard Catalyst.

    REDCap provides automated export procedures for seamless data downloads to Excel and common statistical packages (SPSS, SAS, Stata, R), built-in project calendars, scheduling module, ad hoc reporting tools, and advanced features including branching logic, file uploading, field validations, and calculations.

    Click here to register for this event. Please contact Lisa Horton (E-mail) if you have any questions about this event.

  • October 27, 2010

    arrow-rightBiomedical Imaging Resources: An Introduction

    Time: 4:00 PM - 6:00 PM

    Location: Benjamin Waterhouse Room, Gordon Hall, Harvard Medical School, 25 Shattuck Street, Boston

     

    The Harvard Catalyst Research Navigators and the Harvard Catalyst Translational Imaging Program invite the Harvard community to hear Robert Lenkinski, PhD, and Charles Guttmann, MD, give an overview of Harvard’s biomedical imaging resources and opportunities for collaboration. The two-hour session will feature an overview of available imaging modalities and data analysis. The goal of the evening is to bring together a diverse group of investigators to explore how imaging might be brought to bear on critical biomedical questions.

    A networking session, with refreshments, for participants and speakers to mingle and exchange ideas will follow the discussion.

    Attendance at this event is limited, and registration is required. Attendees should RSVP by October 22, 2010. Click here for registration information.

    The Harvard Catalyst Research Navigators are committed to providing opportunities for collaboration by organizing scientists and clinicians around research resources, areas of investigation, and disease topics. This event is part of the Synergy Series, a series of seminars and workshops designed to increase connectivity in the Harvard Catalyst community.

  • October 29, 2010

    arrow-rightBehavioral Epigenetics

    Location: UMass Boston Campus Center, 100 Morrissey Boulevard, Boston

    This two-day conference will be one of the first to focus on a frontier epigenetics field: Behavioral Epigenetics (i.e., the quest to understand how environmental factors can affect alterations in behavior). Epigenetic effects have been studied in animal models of depression, addiction, schizophrenia and neuro-developmental disorders. Human studies on epigenetics and behavior are being conducted as well. Some psychoactive drugs, such as cocaine or anti-psychotics, also cause changes in some of the co-factors involved in this genetic regulatory system. With an understanding of the molecular mechanisms involved in epigenetic modulation, it might be possible to develop targeted therapies for those individuals in whom it malfunctions.

    This event is jointly sponsored by the New York Academy of Sciences, the Warren Alpert Medical School at Brown University, and the University of Massachusetts Boston.

    Paid registration required, and CME credits are available for attendance. For more information, or to register for this event, visit the conference website.

  • October 30, 2010

    arrow-rightBehavioral Epigenetics

    Location: UMass Boston Campus Center, 100 Morrissey Boulevard, Boston

    This two-day conference will be one of the first to focus on a frontier epigenetics field: Behavioral Epigenetics (i.e., the quest to understand how environmental factors can affect alterations in behavior). Epigenetic effects have been studied in animal models of depression, addiction, schizophrenia and neuro-developmental disorders. Human studies on epigenetics and behavior are being conducted as well. Some psychoactive drugs, such as cocaine or anti-psychotics, also cause changes in some of the co-factors involved in this genetic regulatory system. With an understanding of the molecular mechanisms involved in epigenetic modulation, it might be possible to develop targeted therapies for those individuals in whom it malfunctions.

    This event is jointly sponsored by the New York Academy of Sciences, the Warren Alpert Medical School at Brown University, and the University of Massachusetts Boston.

    Paid registration required, and CME credits are available for attendance. For more information, or to register for this event, visit the conference website.