Events in July 2012

  • July 12, 2012

    arrow-rightEngineered Bone Surfaces: A New Approach for Bone Repair

    Time: 12:00 PM - 1:00 PM

    Location: Seminar Room A, 245 First St., 17th floor, Cambridge, 02142

    Speaker:              S. Adam Hacking, Ph.D.

    Director, Laboratory for Musculoskeletal Research and Innovation

    Orthopaedics

    MGH

     

     

    Summary:  For over 20 years, the application of micro and nano-sized features to the surface of titanium implants has been recognized as a predictable means to enhance osseointegration.  Worldwide, dental and orthopaedic devices with textured surfaces are implanted over 500,000 times annually. Given the extent and duration of clinical use, it is surprising that a biologic rationale for action has not been proposed. My group is interested in biomimetic cues that guide tissue repair.  We considered regions and features associated with bone formation and determined that osteoclast resorption pits and the fracture surfaces were candidates for study.  In this seminar, I will present data that suggests the osseous response to textured implant surfaces may in fact be part of a programmed response to the fracture surface of bone. By taking morphological cues from the fracture surface, we have modified the native ‘smooth’ surface of cortical and cancellous bone to include micro and nano-sized features. We have produced engineered bone surfaces that increase the extent of new bone formation in rat and rabbit animal models.  

    This presentation will provide a review of the fundamentals of surface topography measurement, recent advances in techniques to evaluate the osseous response to biomaterials and will provide data from in vivo and in vitro studies.

     

    For more information or to register, please contact Pam Quattrocchi (email, 617-892-8604)

  • July 19, 2012

    arrow-rightNext Steps for Instructors

    Time: 12:00 PM - 1:30 PM

    Location: Center for Education, Carl J. Shapiro Institute, East Building, Room 202, 330 Brookline Avenue

    The Office of Academic Careers and Faculty Development at Beth Israel Deaconess Medical Center is hosting a series of workshops for post-docs and instructors, led by Dr. Terry Maratos-Flier, that will address the specific factors one must consider for future career development, and the paths forward from the post-doc and instructor experiences. These workshops are open to the Harvard community and affiliated hospitals.

    Workshop 3: Next Steps for Instructors

    This is a workshop to discuss issues regarding promotion at Harvard Medical School versus outside opportunities.

    To register for this workshop, please email the BIDMC Office for Academic Careers and Faculty Development.

    For more information and questions, please email Elizabeth Langley.

  • July 26, 2012

    arrow-rightAn HC-LITT Seminar–Beyond Treading Water: Functional Analysis of Tumor Initiation and Maintenance

    Time: 6:00 PM - 9:00 PM

    Location: HIM, Bray Room, 4 Blackfan Circle, Boston, MA 02115

    Keynote Speaker: Craig J. Ceol, Ph.D.
    Assistant Professor of Molecular Medicine
    University of Massachusetts Medical School

    The Harvard Catalyst Laboratory for Innovative Translational Technologies (HC-LITT) is hosting a seminar examining the genetic pathways that drive the development of cancer, specifically melanoma. Though making up only five percent of skin cancers cases, melanoma is responsible for a large number of the deaths associates with skin cancers, having a particularly poor prognosis when diagnosed in its later stages. Dr. Craig J. Ceol has been working to identify the genetic defects responsible for the growth of tumors, specifically malignant melanoma.

    To attend, please register with HC-LITT Director Winston Kuo (E-mail; 617-432-1894).

    SHOW is produced by Munevar & Associates, Inc.

    The mission of HC-LITT is to provide the Harvard research community with early access to enabling leading-edge genomic and proteomic technologies.

  • July 31, 2012

    arrow-rightAssembling a Mentored Award: NIH K Series

    Time: 09:00 AM - 2:30 PM

    Location: Shapiro Clinical Center, Shapiro Conference Rooms 1A/1B, 90 Binney St, Boston, MA, 02115

    Speakers and Session Topics:

    • Overview and Introduction—Terry Maratos-Flier, MD
    • How to Organize for a Successful K Application—Carol Stearns, Senior Research Administrator
    • Negotiating Support from your Chiefs/Chairs: Your career in the context of your division—Woodrow Weiss, MD
    • The Review Process: What is the NIH looking for?—Aristidis Veves, MD
    • Constructing the Career Development Plan and Mentor’s Statement—Maria Kontaridis, MD
    • Integrating Science Across the Application—Terry Maratos-Flier, MD

    Workshops will include:

    • Organizing mentor letters
    • Grantable specific aims
    • Targeting the NIH reviewers