Biostatistical Science Program Colloquium Series: Effectiveness Research

Posted May 7, 2009

“Effectiveness Research: Bridging the Observational-Experimental Gap”

Philip Lavori, Ph.D.
Professor of Biostatistics
Department of Health Research and Policy
Stanford University

May 26, 2009, 4:00pm – 5:00pm
Center for Life Science Building
Room 11081A
Dana-Farber Cancer Institute
3 Blackfan Circle


With effectiveness research on the front burner, $1 billion in new funding, the prospect of a Universal Electronic Health Record in the near future,  a newly revitalized AHRQ, IOM recommendations in the offing, and the prospect of re-engineered health care financing with evidence-based medicine part of the package, what could go wrong?  In short, nearly everything. I will explore the observational/experimental divide, describe how the lack of a ‘theory of reconciliation’ plays into the hands of those who will oppose any consequential decision-making, and outline a few preliminary steps toward a less adversarial mode of joint inference from experiments and observational studies. I will end with a few risky proposals that might be worth some attention, regarding reintegration of experimental clinical research and clinical care as part of the structure of the health care system of the future.

For additional information on this colloquium or on the Harvard Catalyst Biostatistical Science Program Colloquium Series, contact Elizabeth Jones (E-mail).